How Does Sytropin HGH Spray Work? Ingredients Explained

Every few months, interest in Sytropin spikes in search trends. People see it mentioned in forums or ads and want to know one thing: how is a few sprays under the tongue supposed to affect growth hormone?

In this article, we will explain how Sytropin is meant to work, go through its main ingredients one by one, and tell you what the research says about each. If you want our overall verdict, see our full Sytropin review.

The basic idea

Sytropin does not contain growth hormone. It is a dietary supplement marketed as a secretagogue, a product designed to encourage your pituitary gland to release more of its own growth hormone. The theory is that certain amino acids and other compounds can nudge that release.

It is used as an oral spray under the tongue, typically two sprays in the morning and four before bedtime. The bedtime dose is meant to line up with the natural growth hormone pulse that happens during deep sleep ^[1].

The ingredients, one by one

L-arginine and L-lysine

Arginine is the most studied amino acid for growth hormone. Large oral doses can raise growth hormone at rest in some people. However, when arginine is taken before exercise, the growth hormone response to the workout can be smaller ^[2]. Lysine is sometimes paired with arginine for this purpose. The NIH found the overall evidence for arginine on performance limited and conflicting ^[3].

Ornithine alpha-ketoglutarate

Ornithine is another amino acid linked to growth hormone release in some studies. Evidence in healthy adults at supplement doses is limited.

L-glutamine

Glutamine is abundant in the body and used in clinical nutrition. Its effect on growth hormone at small doses is not well established.

GABA and glycine

Both are popular for relaxation and sleep. Because deep sleep drives natural growth hormone release, sleep support is one plausible indirect pathway, though not proven for this product.

Alpha-GPC

A source of choline often marketed for brain health and exercise. Some small studies have looked at its effect on growth hormone after exercise.

Branched-chain amino acids (L-isoleucine, L-valine) and L-tyrosine

These are common in sports nutrition. Their link to growth hormone is indirect at best.

Mucuna (L-dopa bean extract) and moomiyo extract

Mucuna contains L-dopa, a precursor to dopamine. Dopamine plays a role in growth hormone regulation, which is the rationale for including it. Moomiyo (also known as shilajit) is a traditional mineral-rich resin. Evidence for both at the doses in a spray is limited.

What we do not know

We are not aware of a peer-reviewed clinical trial of the finished Sytropin formula. That means we cannot say how much, if at all, it raises growth hormone, or whether any change leads to noticeable results. Even prescription growth hormone produces only modest body changes in healthy adults ^[4].

Sytropin is sometimes described with “homeopathic HGH” language. The FDA states that no products labeled as homeopathic are FDA approved ^[5].

How to use it sensibly

• Follow the labeled dose. More sprays will not speed things up.
• Use it alongside good sleep, training, and diet, not instead of them.
• Give it 8 to 12 weeks and track sleep, energy, and body measurements.
• Talk to your doctor if you have a health condition or take medication, especially for blood pressure, mood, or Parkinson’s, given the L-dopa content.

If you decide to try it, buy from Sytropin’s official website to get genuine stock and the current guarantee.

Earlier versions of this article called Sytropin clinically tested and FDA approved. Neither was accurate, and we have corrected it.

Affiliate disclosure: Some links on HGHSpecial are affiliate links. We may earn a commission if you buy through them, at no extra cost to you. This does not change what we write about a product.

This article is for information only and is not medical advice. HGHSpecial does not sell prescription HGH or somatropin. Talk to your doctor before taking any supplement, especially if you have a health condition or take medication.

Sources

1. Van Cauter E, Plat L. Interrelationships between growth hormone and sleep. Growth Horm IGF Res. 2000
2. Kanaley JA. Growth hormone, arginine and exercise. Curr Opin Clin Nutr Metab Care. 2008
3. NIH Office of Dietary Supplements. Dietary Supplements for Exercise and Athletic Performance
4. Liu H, et al. Systematic review: the safety and efficacy of growth hormone in the healthy elderly. Ann Intern Med. 2007
5. U.S. Food and Drug Administration. Homeopathic Products